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Health News >> Medications and Drugs >> Statins
Statins News
Statins News From Medical News Today
New research commissioned by Flora pro.activ revealed that two thirds of GPs polled feel that it is very important for patients on cholesterol-lowering medication to also ensure they eat a healthy diet to improve heart health. According to recent NICE guidance on the management of Familial Hypercholesterolaemia (FH), first-line treatment for FH should be statins.
Statins News From Medical News Today
Pfizer announced that in patients with established heart disease, LipitorŪ (atorvastatin calcium) 80 mg not only significantly reduced the relative risk of suffering a first cardiovascular event by 19 percent compared to Lipitor 10 mg but also provided a sustained reduction in the risk of a subsequent second, third, fourth, and fifth cardiovascular event, according to a subanalysis of the five-year Treating to New Targets (TNT) study.
Statins News From Medical News Today
The results of a new observational study presented recently at the showed that patients who stop taking their prescribed statins have a four-fold increased risk of death during the first year following an acute coronary syndrome. The study included 2,234 patients who were prescribed statin therapy after an acute coronary syndrome. Patients were followed for one year after discharge from the hospital.
Statins News From Medical News Today
Genetic lipoprotein disorders are frequently seen in patients with premature coronary artery disease (CAD). An example of strong genetic predisposition is the disorder: familial hypercholesterolemia, where a single gene defect (the low density lipoprotein receptor) contributes to most of the familial expression of CAD.
Statins News From Medical News Today
The results of a new study announced showed that, compared to atorvastatin 20-40 mg therapy, intensive atorvastatin 80 mg therapy significantly reduced the risk of major cardiovascular events, including cardiovascular related death and non-fatal heart attacks, by 40 percent in patients with end-stage coronary artery disease who have already suffered an acute heart attack. The results were presented at the 2008 European Society of Cardiology (ESC) Congress.
Statins News From Medical News Today
Pfizer Inc said that the Eastern Division of the High Court in Copenhagen, Denmark has ruled in the company's favor in challenges to two of its patents covering atorvastatin, the active ingredient in Lipitor. The basic (DK 171,588) and enantiomer (EP 409,281) patents were challenged by generics manufacturer Ranbaxy. The court ruled that the basic patent, which expires in November 2011, would be infringed by Ranbaxy's generic atorvastatin product.
Statins News From Medical News Today
A simple, safe, one-a-day capsule of omega-3 polyunsaturated fatty acids (PUFA) can reduce mortality and admission to hospital for cardiovascular reasons in patients with heart failure. These are the conclusions of the first of two Articles based on the GISSI-HF* study published early Online and in an upcoming edition of The Lancet. The second Article concludes that statin treatment with rosuvastatin does not affect clinical outcomes in patients with chronic heart failure.
Statins News From Medical News Today
Statins, a group of drugs used to lower cholesterol levels in people with or at risk of having cardiovascular disease, should be used more frequently to combat the adverse cardiovascular outcomes from atherosclerosis, according to new research published in the September 2008 issue of the Journal of Vascular Surgery.
Statins News From Medical News Today
Patients discontinuing statin medication following an acute myocardial infarction (AMI) increase their risk of dying over the next year, say researchers at McGill University and the McGill University Health Centre (MUHC). Their study was published in a recent issue of the European Heart Journal. Using data on British patients who survived an AMI and were still alive three months later, Dr.
Statins News From Medical News Today
Low levels of LDL cholesterol as well as high levels are associated with cancer in patients with type 2 diabetes, found a prospective cohort study published in CMAJ.
Statins News From Medical News Today
Young researchers presented innovative, early-stage research at the 16th Annual Summer Research Conference, a collaborative project of the AUA Foundation and the Society for Basic Urologic Research (SBUR). The AUA Foundation hosted the forum for young investigators to showcase and discuss the most cutting-edge research in sexual medicine.
Statins News From Medical News Today
Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, announced that new pre-clinical data from its hypercholesterolemia program was published in Proceedings of the National Academy of Sciences (Frank-Kamenetsky, M., et al (August 11, 2008) Proc. Natl Acad. Sci. USA, 10.1073/pnas.0805434105).
Detailed Results From The SEAS Study To Be Presented At European Society Of Cardiology Congress 2008
Statins News From Medical News Today
Topline results from the SEAS trial, which were first disclosed publicly at a press conference in London on 21st July, have since then caused heated reaction. The results showed that reducing levels of LDL-cholesterol with a proprietary combination of simvastatin and ezetimibe in patients with aortic stenosis had no more effect on major cardiovascular events (the study's primary endpoint) than with placebo.
Statins News From Medical News Today
Pfizer Inc announced that, in patients with heart disease, type 2 diabetes and chronic kidney disease, LipitorŪ (atorvastatin calcium) 80 mg significantly reduced the risk of major cardiovascular events, including heart attack and stroke, by 35 percent compared with Lipitor 10 mg. This finding is from a subanalysis designed and completed following the closure of the five-year Treating to New Targets (TNT) study in patients with existing coronary heart disease.
Statins News From Medical News Today
Karo Bio has successfully completed a 12 week phase IIb study of eprotirome (KB2115) given to patients with dyslipidemia (elevated blood lipids). These patients were already on statin treatment. Data show that eprotirome induced a statistically significant and clinically relevant lowering of serum LDL-cholesterol, triglycerides and lipoprotein (a) and was safe and well tolerated.
Statins News From Medical News Today
Nymox Pharmaceutical Corporation (NASDAQ:NYMX) holds U.S. and global patent rights for the use of statin drugs for the prevention and treatment of Alzheimer's disease (AD), including for patients at risk for AD because of vascular-related risk factors or disease. An important new study has found that people who take statin drugs were about half as likely to develop dementia or clinically significant cognitive impairment as those who did not use statins (Neurology July 29, 2008; 71:344-355).
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A US study that followed over 1,500 older Mexican Americans for 5 years found that statin users were about half as likely to develop dementia, or to have cognitive impairment without dementia, as those who did not use statins. Statins are normally prescribed for lowering LDL or "bad" cholesterol.
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Statins are increasingly hitting the headlines as a potential cure for dementia. The jury is still out on how effective they are, but this study adds to growing evidence that they may have some benefits. All drugs have some side-effects so it is important to seek professional advice about medication.
Statins News From Medical News Today
People at high risk for dementia who took cholesterol-lowering statins are half as likely to develop dementia as those who do not take statins, a new study shows. The study consisted of older Mexican-Americans in Sacramento, Calif.
Statins News From Medical News Today
New research from over 223,000 patients published in the Primary Care Cardiovascular Journal (PCCJ)1, suggests that total cholesterol (TC) levels in statin-treated UK patients are higher than that of the general population. The recent Health Survey for England (HSE 2006) 2 found that the mean TC was 5.3 mmol/L in men and 5.4 mmol/L in women. This is in contrast to the average TC of 6.
Statins News From Medical News Today
For patients receiving kidney transplants, treatment with cholesterol-lowering "statin" drugs may lead to longer survival, reports a study in the November 2008 Journal of the American Society of Nephrology (JASN). "Statin therapy is well established for the primary and secondary prevention of cardiovascular disease in the general population, but its effectiveness in patients with kidney disease is unclear," comments Dr.
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The University of Oxford Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU) proposed that the hypothesis-generating results of the SEAS trial of ezetimibe should be tested by reviewing the combined cancer results from the SHARP and IMPROVE-IT trials of ezetimibe, and reporting on the overall findings to the relevant regulatory authorities, independently of the drug manufacturers.
Statins News From Medical News Today
The SEAS (Simvastatin and Ezetimibe in Aortic Stenosis) study has investigated the effects of intensive cholesterol lowering with the combination of simvastatin (40 mg daily) and ezetimibe (10 mg daily) in patients with aortic stenosis. Aortic stenosis (which involves partial blockage of the aortic valve in the heart) is a relatively common disease among older people in Western populations. Left untreated, it can progress to death from heart failure or cardiac arrest.
Statins News From Medical News Today
Cancer is a disease characterized by important metabolic alterations. Not only do these adaptative changes give higher proliferative capacity to cancer cells, but they also contribute to higher resistance to chemotherapeutic agents. The research group led by Dr.
Statins News From Medical News Today
Merck Sharp & Dohme (MSD) announced that TREDAPTIVE? (nicotinic acid/laropiprant, MSD) 1 g/20 mg modified-release tablets, a new lipid-modifying therapy for patients with dyslipidemia and primary hypercholesterolemia, has been approved for marketing in the European Union (EU), Iceland and Norway. TREDAPTIVE combines nicotinic acid (niacin) and laropiprant, a novel flushing pathway inhibitor.
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