Yale researchers have identified an unusual molecular process in normal tissues that causes RNA molecules produced from separate genes to be clipped and stitched together. The discovery that these rearranged products exist in normal as well as cancerous cells potentially complicates the diagnosis of some cancers and raises the possibility that anti-cancer drugs like Gleevec could have predictable side effects. The work is reported in the journal Science.

In what has been heralded as a significant breakthrough in the fight against two of the world's deadliest cancers, US scientists have mapped complete genetic blueprints comprising more than 20,000 genes in 24 pancreatic cancers and 22 brain cancers, including not only individual gene mutations but also their interlinked pathways which sustain tumour development and growth.

Why is it that the origins of many serious diseases remain a mystery? In considering that question, a scientist at the University of California, San Diego School of Medicine has come up with a unified molecular view of the indivisible unit of life, the cell, which may provide an answer. Reviewing findings from multiple disciplines, Jamey Marth, Ph.D.

Serum microRNAs (miRNAs) can serve as biomarkers for the detection of diseases including cancer and diabetes, according to research published online this week in Cell Research. The findings pave the way for a revolutionary non-invasive diagnostic tool. miRNAs are a class of naturally occurring small non-coding RNAs that have been linked with cancer development.

Human arteries play distinct roles in the immune system depending on their anatomical location, researchers at Emory University School of Medicine have discovered. Their findings explain why vascular diseases affect different parts of the arterial network and could help doctors fine-tune the treatment of such diseases as atherosclerosis and vasculitis. Atherosclerosis causes heart attacks and strokes because it occurs preferentially in arteries supplying the heart and the brain.

Imagine having to copy an entire book by hand without missing a comma. Our cells face a similar task every time they divide. They must duplicate both their DNA and a subtle pattern of punctuation-like modifications on the DNA known as methylation. Scientists at Emory University School of Medicine have caught in action one of the tools mammalian cells use to maintain their pattern of methylation.

Out of the 3 billion genetic letters that spell out the human genome, Yale scientists have found a handful that may have contributed to the evolutionary changes in human limbs that enabled us to manipulate tools and walk upright.

The tumor suppressor gene pRb2/p130 may provide the first independent prognostic biomarker in cases of soft tissue sarcoma (STS), according to an international collaboration of researchers, including scientists at the Sbarro Institute for Cancer Research and Molecular Medicine at the College of

Scientists studying human Swedish twins and voles have discovered a gene variant involved in producing a hormone that affects monogamy in animals whereby men with two copies of the variant were twice as likely to have had a relationship crisis with their spouse or partner in the last 12 months than men who did not carry the variant.

Yale molecular and evolutionary biologists in collaboration with Department of Energy scientists produced the full genome sequence of Trichoplax, one of nature's most primitive multicellular organisms, providing a new insight into the evolution of all higher animals.

Why are not all hosts resistant to their parasites? Possibly, because the necessary defences are costly. Evolutionary biologists distinguish between long-term, evolutionary costs of possessing defences against parasites, and the short-term costs of using them. Yet they typically focus on the former in the search for constraints on the evolution of resistance. This article shows that short-term costs may be of equal evolutionary importance.

Humans live in societies consisting of a number of levels, from core social groups of 3-5 close relatives termed support cliques to larger, looser aggregations such as tribes that contain over 1000 individuals. Recent research has shown that these networks have a consistent structure; each subsequent level of the networks is 3-4 times the size of the preceding smaller grouping level.

The many recent reports documenting the therapeutic efficacy of short interfering RNAs (siRNAs) in animal models of human disease may actually be describing non-specific therapeutic effects related to the ability of siRNA to activate an immune response, according to a paper in the September 2008 issue (Volume 19, Number 9) of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc.

Reporting this week in the Archives of General Psychiatry, researchers at the Johns Hopkins University School of Medicine have uncovered for the first time molecular circuitry associated with schizophrenia that links three previously known, yet unrelated proteins. "This is very exciting because until now the many known genetic factors implicated in this condition were not connected in any way," says Akira Sawa, M.D., Ph.D.

UCSF scientists have discovered that a gene controlling whether blood vessels differentiate into arteries or veins during embryonic development is linked to a vascular disorder in the brain that causes stroke.

The evolution of altruism poses a problem in evolutionary theory: How can natural selection favour individuals that carry altruistic traits over those carrying selfish traits? This paper presents a simple framework that highlights the most fundamental requirement common to all competing theories for the evolution of altruism: sufficient assortment between carriers of helping traits and help from other individuals in the altruists' interaction environments.

Amounts of DNA per genome vary more than 7,000-fold among animal species. Some groups such as amphibians exhibit a large range in genome size, whereas others like birds are limited to relatively small genomes. Genome size correlates positively with cell size, which is associated with an inverse relationship between DNA amount and metabolic rate in mammals and birds.

Parents expect to pass on their eye or hair color, their knobby knees or their big feet to their children through their genes. But they don't expect to pass on viruses through those same genes. New research from the University of Rochester Medical Center shows that some parents pass on the human herpes virus 6 (HHV-6) to their children because it is integrated into their chromosomes.

One of the concerns of citizens with the development and use of genetically engineered mosquitoes in the fight against dengue fever and malaria is the fact that most of the current approaches result in released engineered strains remaining in the environment. We provide a novel approach that enables self-limiting spread of an engineered construct and describe its population genetic and mechanical properties.

A study of Crohn's disease and ulcerative colitis in children has identified a gene that influences whether children get these diseases early in life, and points to a potential new target for treatment. The findings of the international team that performed the study were published online this week by the journal Nature Genetics.

Scientists at the Swedish medical university Karolinska Institutet have found a link between a specific gene and the way men bond to their partners. The results, which are presented in the scientific journal PNAS, can lead to a better understanding of such problems as autism and social phobia.

Scientists at Wake Forest University School of Medicine and colleagues who are studying a prostate cancer gene called HNF1B have found a second independent site within the HNF1B gene on chromosome 17 (17q12) increasing the number of genetic variants that may contribute to risk of developing the disease.

The children of older aged fathers may have an increased risk of bipolar disorder (BPD), according to a report released on September 1, 2008 in the Archives of General Psychiatry, one of the JAMA/Archives journals. A common and intense mood disorder, people who are bipolar often experience episodes of mania and depression. There are few previously identified risk factors for bipolar disorder, one of which is a family history of psychotic disorders.

Researchers at the Translational Genomics Research Institute (TGen) has announced a new approach to treating endometrial cancer patients that not only stops the growth of tumors, but kills the cancer cells. In a potentially major breakthrough, TGen scientists and collaborators at Washington University School of Medicine in St.

National Institutes of Health's (NIH) National Institute of Mental Health (NIMH) researchers have found out that gene p

Eczema is a type of skin condition that affects millions of people. Scientists at the University of Dundee have discover

Did you know that the genetic code of chimpanzees is so much alike the code of humans, almost a 98% similarity, and perh

American teenagers are now easing their emotional pain by taking Oxycontin, a prescription painkiller. Later on for a mo

Speculation that the Food and Drug Administration will give a nod for the generic version of Vancocin caused shares in V

UK Biobank has launched the world's largest medical experiment at Altrincham, Cheshire. It has already sent

Researchers in the Johns Hopkins University School of Medicine said that genetic material in the yeast cell guards the g

A U.S. Census study found that the Americans who are old today are much healthier as compared to those in the past, have

It has been known for a long time that maleness in most mammals relates to aggressive behavior and a less nurturing tend

Scientists have identified those two genes that were responsible for the cause of blindness that affects millions of old

New research led by New York's Columbia University suggests that almost three-quarters of the cases of age-related macul

When children turn into adults, some genes involved in controlling their blood pressure change as well. This is as per a

Researchers from Duke university Medical Center have established that an individual's health and well being is largely i

Dr. Harold Snieder, genetic epidemiologist at the Medical College of Georgia said that genes that control blood pressure

A mechanical engineer at Purdue University is to build robots that could make an operating procedure less expensive and

Scientists at University of California have gained valuable insights about the differentiation of embryonic stem cells o

Researchers at Johns Hopkins University and the Institute of Bioinformatics in Bangalore, India, created a database of m

European regulators have not given the green signal to a drug produced in the milk of genetically engineered farm animal

A recent study by researchers from the University of Wisconsin-Madison and University of Utah said that taste genes play

A new technique has been developed to identify and localize the presence of tiny iron oxide particles associated with ne

What's in a Surname? There's a lot you can decipher from surnames, especially from those men who share similar surnames.

Women are too busy building careers, and raking in the moolah, with no time or the inclination to make babies that resul

The SRY or the sex determination gene, that plays a crucial role in deciding if an embryo should develop into a male or

Breast cancer is the second-biggest killer of women in UK. The recent reports that many women will be barred from buying

A new research at the National Institutes of Health (NIH) said that Heart health risk can be prevented by modifying the

Recombinomics, a premier research institution has warned about the possibility of a hemagglutinin gene mutation with res

Calif : A woman who is just three feet tall and 37 pound in weight prior to pregnancy, has delivered a healthy baby boy

A bully seems to have an unabating negative influence on the victim. Scientists have observed this unnerving effect of b

In order to better understand the role of genetic and environmental factors in the incidence of common diseases, the Uni

Stiff competition offered by generic drug makers may well eat into the profit figures of GlaxoSmithKline, according to c

It's all in the Genes they say. In the first ever threadbare genetic study of Alzheimer's, reports have it that late on

There is every possibility that there could be a common gene which gives rise to Alzheimer's disease, according to resea

The drug Macugen is found to be effective in treating wet age related macular degeneration disease which is a progressiv

Researchers in Scotland are planning to recruit 50,000 people as a part of a large study called as Generation Scotland.

An exhaustive genetic study conducted on more than 3000 people has helped solve one of the ancient mysteries associated

Stem cells from cord blood are to be used for regeneration of broken bones in a new multicentric project at the cost of

Mrs. May Murphy from Glasgow was confirmed to have committed suicide five months ago using a lethal dose of drugs. Mrs.

It is a well established fact that any genetic alterations in either the BRCA1 or BRCA2 gene can predispose to breast ca

A genetic mutation has been identified by researchers which is responsible for over 20% of the incidences of Parkinson's

Professor Bharat Ramratnam, Assistant Professor, Brown Medical School is exploring the beneficial properties of Lactic a

Certain genes in a person can make him more predisposed where smoking is concerned, according to a new research. This re

Researchers at Barrow Neurological Institute in Phoenix have discovered that the key to visual awareness is located in t

It has bugged researchers for long to detect the cause of blindness-inducing neurodegenerative diseases such as age-rela

University of Minnesota Medical School researchers have reason to cheer. A novel discovery which could affect h

A novel gene therapy is being developed by scientists belonging to the Northwestern University targeted at turning off s

In US a team of researcher from the university of Texas Southwestern Medical Center in Dallas reported that the gene NR1

Researchers from the Northwestern University are developing a unique genetic therapy by which they can switch off a gene

Researchers at Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove

A study conducted by Xin-Yun Lu, PhD and colleagues of the University of Texas Health Science Center found that Leptin w

Heart disease claims about 7 million lives every year, according to the WHO. Scientists have been trying to identify the

Scientist working at the DeCode Genetics Inc (Reykjavik company) was successful in identifying the gene that affects one

Professor Sina Bavari and team from the U.S. Army Medical Research Institute of Infectious Diseases have found that anti

A research study has revealed that one third of the moles which are seen among elderly Australians who run the risk of c

Bipolar disorder is otherwise called as maniac-depressive illness. The disease incidence is about one in fifty. But the

Australian researchers are reported to have identified a gene which gives rise to bipolar disorder in human beings. Othe

Scientists have identified six genes which may be involved in heightening the risk of contracting Alzheimer's disease. T

The risk for alcohol dependence is greatly increased if an individual has a variant form of a gene that controls the bit

In this era of personalized medicine, one should reevaluate new medicines and treatments for cancer, says Prof. Donald B

The caspase-8 gene prevents the metastasis of the neuroblastoma. This research was conducted at St. Jude Children's Rese

HIV/AIDS has been haunting man for many years. There is a fear instilled by the disease among the people, as the disease

Women are more prone to depression than men, and this may be due to genetic factors, according to a research published i

The Journal of Science has published a research report which has identified the gene responsible for regulating memory,

Researchers at the University of Pittsburgh have demonstrated that loss of DNA repair enzyme's activity in mouse cel

Consumption of a high fat diet has been found to suppress the activity of GnT-4a gene, an enzyme that regulates ins

An insurance scheme which has received the approval of the Government is attracting brickbats and bouquets. As many as 2

A research was conducted by Selda Samakoglu and colleagues at the Memorial Sloan-Kettering Cancer Center. This research

Scientists have identified two genes essential for the development of muscles.Da-Zhi Wang and other researchers of the U

In a new study that is to appear in the January issue of Nature Reviews Genetics, a Johns Hopkins researcher suggests th

New genes such as microRNAs (miRNAs) belong to the newly discovered group of genes. Researchers working at the Universit

Stem cell therapy research can be carried out in terminally ill patients who are dying of neurodegenerative disorders as

A gene which is connected to Parkinson's disease can serve to keep brain cells alive. This has been revealed by the Univ

The macular degeneration which is directly related to age can be reduced by eating carrots which contain the nutrient be

Professor Joanne Murabito and team have reported that the risk of heart disease increased in middle aged adults who have

Muscular dystrophy may also be cured by a gene therapy technique which has been promising where hemophilia and skin dise

The US Food and Drug Association (FDA) has approved Aurobindo Pharma Limited to produce the generic version of oral Stav

India could make her own generic drug version of the Tamiflu anti-flu drug. Roche who holds the patent for Tamiflu drug

A strong genetic link has been discovered by the University of Washington researchers between obesity and asthma. The re

The drinking behavior of tobacco users is related to the same chromosome regions which are connected with addiction to a

Researchers at the University of Michigan and the Mayo Clinic say that the flagship breast cancer drug, tamoxifen might

Women who are undergoing tests to detect if they harbor a gene that puts them at increased risk of breast cancer are fac

The Quebec strain of C.difficile's genetic code is reported to have been cracked by the researchers from the McGill Univ

If all the ways genes that go the wrong way to cause cancer were to form a a dictionary, scientists can decipher only p

Research conducted by George S. Zubenko, MD, PhD, Professor of Psychiatry and Biological Sciences at the University of P

A research in the United Kingdom by Dr Foster and his team reported that by 2031 there will be an increase in the number

The increasing number of people resorting to sleeping pills for treatment of insomnia has no doubt prompted for inventio

A healthy brain can be maintained by a person at old age through activities that exercise the brain like a daily crosswo

Professor Karen Gripp and his team from DuPont Hospital studied genetic mutations in H-ras gene which lead to Costello S

Scientists from University of California have developed new technique for regeneration of injured nerve cells which coul

A Research headed by the vascular surgeon Rajabrata Sarkar, MD, PhD, at the San Francisco VA Medical Center has unravele

Researchers from University of North Carolina have identified a molecule Ack1, which is responsible for suppressing the

Bacteria, like other living organisms, are exposed to ever-changing environments, oxidative stress, and worst of all, an

This new treatment claims to treat the cancer by 'gene silencing.' This process apparently turns off a single gene in a

In a medical breakthrough, Australian researchers have discovered that hereditary blood clotting disorders increase the

Queensland University researchers have ventured into a new approach called 'gene silencing' for the treatment of cervica

Eating specific food could change your genes, say researchers after success in a rodent study. Researchers Moshe Szyf,

Vietnamese scientists have successfully decoded the gene of the deadly H5N1 virus, an article in the local newspaper You

Researchers have found that co-infection of two genetic diseases Thalassemia and Sickle Cell anemia make the patients su

A definitive link has been established between age-related macular degeneration and the genetic mechanisms underlying th

In a breakthrough, which could eventually lead to a practical and cost effective new way to combat the HIV virus, scient

A new study appearing in the November 1, 2005 issue of The Journal of Clinical Oncology (JCO), says that a new gene prof

John Cacioppo and researchers have found that the habit of being lonely is genetically programmed and it runs in to fami

Embryonic genetic testing is boosting the success rate of IVF pregnancies. However, the capacity to screen for non-life

Researchers are finding out the various factors which are responsible for malaria infection and their susceptibility and

DNA of chimps and humans share a 98% similarity and the small difference of 2% dissimilarity between chimps and humans c

Scientists from University of Wisconsin, US and University of Tokyo, Japan have found a faster and reliable method of va

Researchers at Yale University have discovered the 'DCDC2' gene associated with dyslexia. Dyslexia causes learning disab

WASHINGTON. In a breakthrough research scientists have for the first time been able to turn the embryonic stem cells in

Dr Paul Brennan and his team from International Agency for Cancer Research scientists (IACR) have reported in the Lancet

A report published in The Lancet has implicated a defective gene called Chek2 in the development of breast cancer in wom

Researchers at the University of Pittsburgh have successfully treated heart failure in an animal model that is genetical

Though there is lot of controversies over the usage of Generic drugs in India and other countries. Now US based compan

Hunter and colleagues have identified a candidate gene, Sipa1, with an amino acid polymorphism that influences metastasi

Infectious Diseases Society of America (IDSA), has reported that the survival rate of patients infected with HIV has ris

Richard Wenzel and his colleagues from United Kingdom have found a new antibiotic tigecycline which belongs to the famil

Farmers and different organizations from Asian countries are protesting against the introduction of genetically engineer

Recently, a study has been launched, which, if fruitful, may enable future generations to heal without scarring and grow

London, Oct 11 In an important research development a genetically modified mosquito has been created that wipe out natur

A gene on chromosome 15 regulates inflammation according to scientists. Inflammation has a role to play in a wide range

Dr Moorman and his colleagues from Southampton University have found a new gene based test for identifying DNA fusion, i

It has been found that skin cancer could actually be caused as a result of a defect in just a single gene. The finding

Scientists from Barts and London Queen Mary's School of Medicine, London has employed gene testing technology by using g

Researchers have found that gene mutation is associated with the neurological disorder called hereditary neuralgic amyot

Research shows that gene variations make some people vulnerable to suffer from the dreaded disease of multiple sclerosis

Researchers had found that there exists a major link between a risk gene for stroke and incidence of stroke in young adu

Researchers from the University of North Carolina at Chapel Hill, in the current issue of PLoS Computational Biology, ha

Researchers from the University of Texas, M.D. Anderson Cancer Center, Houston have found a gene, which on mutation or d

Expiry of Patent period for branded Zidovudine in US has lead to approval of FDA for new generic version of AZT, which w

Researchers from Memorial Sloan Kettering Cancer Center, New York has reported that Women with a strong family history o

Researchers from the University of Michigan Kellogg Eye Center had developed a rapid genetical testing to diagnose eye d

Investigators and patients alike look forward to the day when it will be possible to correct the effects of abnormal gen

Dr. Richard Vile, Mayo Clinic Molecular Immunologist and his team has found a new virus based gene therapy delivery syst

The risk of pre-eclampsia in pregnant women may be genetical and both the parents' genes of the pregnant lady may have t

Increasing criticism is faced by AIDS generic drugs usage to treat HIV infections, due to non-compliance with clinical a

The problem of increasing risk to bone fractures may be due to genetical reasons, said a study in the September issue of

Rare eye disorder from genetic sources can also be responsible for other effects in the brain and fetal cardiovascular d

Professor Hiroaki Matsubara and colleagues from Kyoto University Hospital has regenerated stem cells from cardiac muscle

Looks like it is time men got their share from women in the inheritance of cancer as well. A genetic mutation linked wit

Researchers in the US have developed a way to print DNA (Deoxyribonucleic Acid), which they say will one day make geneti

Researchers from Johns Hopkins had discovered the gene expression responsible for extreme farsightedness in people. b

Investigators from UCLA had found that the there is a marked difference between the sensations generated by cocaine and

Research studies have shown that use of general anesthesia for heroin detoxification is no better when compared to other

Researchers of Cold Spring Harbor laboratory have discovered that the loss of a gene called p63 accelerates the process

New research points out that the difference in genes might be responsible for the way patients suffering from attention

For the first time, a gene linked to the disease tuberculosis has been identified which, is held to control the onset of

Research suggests that the reason why elderly population differs in their ability to exercise for better physical abilit

Researchers from University of Utah School of Medicine had reported that a key process in gene regulation could occur in

The Centre for Cellular and Molecular Biology (CCMB), Hyderabad has unraveled the mystery behind gene silencing, paving

Research shows that elderly people who exercise regularly and have a certain gene variety have the tendency to have fewe

Kylie minogue, the famous pop star knowing or unknowingly has generated awareness about breast cancer. Her may breast ca

Four new genes have been identified which could presumably play a major role in the development of breast cancer, b

Researchers had found a new technique to control genetic expressions by silencing some expressions of the gene. This t