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Health News >> Diseases and Conditions >> Neurological Disorders >> Parkinsons Disease
Parkinsons Disease News
Parkinson's Disease News From Medical News Today
Levodopa has long been proven to provide the greatest relief of all available medications in the treatment of Parkinson's disease. It also is the most cost-effective drug for managing the full range of problems associated with this chronic neurological disorder, which affects an estimated one million Americans. In the Dec. 4 issue of the New England Journal of Medicine, Henry Ford Hospital neurologist Peter A. LeWitt, M.D.
Parkinson's Disease News From Medical News Today
Schering-Plough Corporation (NYSE: SGP) reported that preladenant, its novel and selective adenosine2a receptor antagonist, met the primary endpoint in a Phase II dose-finding trial in patients suffering from moderate to severe Parkinson's disease experiencing motor fluctuations and abnormal involuntary movements (dyskinesias). The trial results were presented at the company's 2008 R&D Update meeting being hosted for analysts and portfolio managers at company headquarters.
Parkinson's Disease News From Medical News Today
Ceregene, Inc., a biopharmaceutical company, reported clinical data from a double-blind, controlled Phase 2 trial of CERE-120 in 58 patients with advanced Parkinson's disease. The trial did not demonstrate an appreciable difference between patients treated with CERE-120 versus those in the control group.
Parkinson's Disease News From Medical News Today
A new study by Narendra et al. suggests that Parkin, the product of the Parkinson's disease-related gene Park2, prompts neuronal survival by clearing the cell of its damaged mitochondria. "[This is] an exciting new discovery that links the fields of mitochondrial quality control and the genetics of Parkinson's disease (PD)," writes Heidi McBride of the University of Ottawa Heart Institute.
Parkinson's Disease News From Medical News Today
Schering-Plough Corporation (NYSE: SGP) reported that preladenant, its novel and selective adenosine2a receptor antagonist, met the primary endpoint in a Phase II dose-finding trial in patients suffering from moderate to severe Parkinson's disease experiencing motor fluctuations and abnormal involuntary movements (dyskinesias). The trial results were presented at the company's 2008 R&D Update meeting being hosted for analysts and portfolio managers at company headquarters.
Parkinson's Disease News From Medical News Today
Researchers have identified a stage during dopamine neuron differentiation that may be an ideal time to collect human embryonic stem cells for transplantation to treat Parkinson's disease, according to data presented at Neuroscience 2008, the 38th annual meeting of the Society for Neuroscience. Lorraine Iacovitti, Ph.D.
Parkinson's Disease News From Medical News Today
Researchers have identified a stage during dopamine neuron differentiation that may be an ideal time to collect human embryonic stem cells for transplantation to treat Parkinson's disease, according to data presented at Neuroscience 2008, the 38th annual meeting of the Society for Neuroscience. Lorraine Iacovitti, Ph.D.
Curry Spice Curcumin And Parkinson's Disease? Protects Against A53T Alpha-synuclein-induced Toxicity
Parkinson's Disease News From Medical News Today
Johns Hopkins Researchers at Neuroscience 2008 - Curcumin, derived from the curry spice turmeric, has strong antioxidant and anti-inflammatory properties. Both oxidative damage - damage caused by oxygen - and inflammation have been implicated in nerve cell death associated with Parkinson's disease. Now, researchers at the Johns Hopkins University School of Medicine have shown in a laboratory model of Parkinson's disease that curcumin does protect cells from dying.
Parkinson's Disease News From Medical News Today
Mayo Clinic (http://www.mayoclinic.org) researchers have developed a method to reduce the production of alpha-synuclein in the brain. Alpha-synuclein is a protein that is believed to be central to the cause of Parkinson's disease (http://www.mayoclinic.org/parkinsons- disease).
Parkinson's Disease News From Medical News Today
Researchers at Southern Methodist University (SMU) and The University of Texas at Dallas (UTD) have identified a group of chemical compounds that slow the degeneration of neurons, a condition behind old-age diseases like Alzheimer's, Parkinson's and amyotrophic lateral sclerosis (ALS). Their findings are featured in the November 2008 edition of Experimental Biology and Medicine. SMU Chemistry Professor Edward R.
Parkinson's Disease News From Medical News Today
A new study being published in this Friday's online edition of Cell will help answer the question, what causes Parkinson's disease? One of the most pressing questions in the medical research into Parkinson's disease is what causes the sensitive cells in the brain to die in the first place.
Parkinson's Disease News From Medical News Today
Researchers from the Peninsula Medical School, Plymouth Hospitals NHS Trust and the University of Plymouth, have received a grant funding of £2million over the next five years from the National Institute for Health Research (NIHR) to investigate new ways of developing clinical trials for the treatment of Alzheimer's disease and Parkinson's disease.
Parkinson's Disease News From Medical News Today
Medical experts from UK charities concerned about the rise in miracle cure stories, wonder drugs and so-called breakthrough therapies have teamed up to produce a guide that explains how to tell the beneficial from the bogus.
Parkinson's Disease News From Medical News Today
Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, announced today that it has published new research with collaborators at Mayo Clinic in the journal Molecular Neurodegeneration. The new pre-clinical findings demonstrate durable therapeutic silencing of the alpha-synuclein gene when small interfering RNAs (siRNAs), the molecules that mediate RNAi, are administered by direct delivery to the CNS in mice.
Parkinson's Disease News From Medical News Today
The goal in treating patients with gout is to reduce acute attacks by lowering serum urate levels, which are usually high in this disease. At the same time, high serum urate levels have been shown to lower the risk of developing Parkinson's disease (PD). A new study compared the safety and efficacy of febuxostat, a new drug being developed for gout that was recently approved for use in Europe, and a commonly used drug that has been around for years.
Parkinson's Disease News From Medical News Today
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS), disrupt the quality of life for patients, put a tremendous burden on family caregivers, and cost society billions of dollars annually. The most consistent risk factor for developing neurodegenerative disease is aging.
Parkinson's Disease News From Medical News Today
Novartis Pharmaceuticals Corporation today announced the launch of two new FDA-approved dosage strengths of Stalevo(R) (carbidopa, levodopa and entacapone), which is indicated for certain people with Parkinson's disease who experience end-of-dose "wearing off". The approval of Stalevo 75 and 125 tablets (18.75 mg carbidopa, 75 mg levodopa, 200 mg entacapone and 31.
Parkinson's Disease News From Medical News Today
The Parkinson's Disease Foundation (PDF) is pleased to announce an award of $150,000 toward investigations studying the potential of individualized stem cell therapy to treat Parkinson's disease (PD). The grant will support the research of Marina Emborg, M.D., Ph.D., and Su-Chun Zhang, M.D., Ph.D., both of the University of Wisconsin, Madison.
Parkinson's Disease News From Medical News Today
The Parkinson's Disease Society (PDS) today welcomed Alan Johnson's announcement to allow patients to self-refer to physiotherapists and allied health professionals. Steve Ford, Chief Executive of the PDS said: "Alan Johnson's announcement is certainly a step in the right direction. NICE's Parkinson's guidelines recommend speedy access to therapy services that can make a real difference to the quality of life of someone with a long term progressive illness.
Parkinson's Disease News From Medical News Today
Representatives from the Collaborative on Health and the Environment (CHE) and Parkinson's Action Network (PAN) today released an executive summary of the consensus statement on "Parkinson's Disease (PD) and the Environment," which was recently published on-line in
Parkinson's Disease News From Medical News Today
Addex Pharmaceuticals (SWISS: ADXN) announced that it has completed the first part of a two-part Phase I clinical trial to evaluate the newly developed modified release formulation of ADX48621. ADX48621 is scheduled to start a Phase IIa proof of concept study for the treatment of levodopa associated dyskinesia in Parkinson's disease during the first half of 2009.
Parkinson's Disease News From Medical News Today
Recently, the University of Missouri Department of Psychological Sciences introduced an addition to their field of research with the opening of the Brain Imaging Center (BIC). The BIC will allow MU researchers to conduct behavioral research on diseases that can have tremendous impact, including Parkinson's disease, autism, schizophrenia and other neurocognitive disorders using magnetic resonance imaging (MRI) technology.
Parkinson's Disease News From Medical News Today
Neurogen Corporation (Nasdaq: NRGN) today announced positive top-line results from two Phase 2 clinical trials in restless legs syndrome (RLS) and Parkinson's disease with the Company's dopamine partial agonist, aplindore. These studies were the first in which aplindore has been evaluated in RLS and Parkinson's disease. In each study, aplindore demonstrated highly significant efficacy and was well tolerated.
Parkinson's Disease News From Medical News Today
Dr Kieran Breen, Director of Research, Parkinson's Disease Society said: "Studies like this provide clues as to what happens to the brain of people living with Parkinson's and the potential link between the condition and a Vitamin D deficiency.
Parkinson's Disease News From Medical News Today
A majority of Parkinson's disease patients had insufficient levels of vitamin D in a new study from Emory University School of Medicine. The fraction of Parkinson's patients with vitamin D insufficiency, 55 percent, was significantly more than patients with Alzheimer's disease (41 percent) or healthy elderly people (36 percent). The results are published in the October issue of Archives of Neurology.
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