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Liver Disease and Hepatitis News

Improved Tool To Rank Sickest Patients Waiting For Liver Transplants Developed By Mayo Clinic

Liver Disease / Hepatitis News From Medical News Today

Mayo Clinic researchers have developed an improved statistical model that could help ensure that the sickest patients receive liver transplants first. Researchers found that including serum sodium concentration in the statistical model now used could reduce by 7 percent the number of patients (as many as 50 people) who die each year while waiting for a liver transplant. Serum sodium levels can be measured with a blood test.

Cellvizio(R) Imaging System Improves Bile Duct Cancer Detection According To A New Study In Clinical Gastroenterology And Hepatology

Liver Disease / Hepatitis News From Medical News Today

A new imaging system that allows physicians to examine tissue at the cellular level from inside the body may now enable them to more effectively diagnose cancer of the bile ducts, according to a new study in the September 2008 issue of the journal Clinical Gastroenterology and Hepatology. This cancer, medically known as cholangiocarcinoma, is one of the most difficult to detect and treat.

Health Care Professionals Seeing More Children With Fatty Liver Disease; Condition Prevalent Among Hispanics

Liver Disease / Hepatitis News From Medical News Today

As many as 2% to 5% of children older than age five -- most of whom are obese -- are thought to have nonalcoholic fatty liver disease, and the condition seems to be most prevalent among Hispanic children, the AP/San Mateo Daily Journal reports.

Walter Reed Evaluation Concludes OraQuick(R) HCV Test Is Preferred Over Other Rapid Tests

Liver Disease / Hepatitis News From Medical News Today

OraSure Technologies, Inc. (NASDAQ:OSUR), a market leader in oral fluid diagnostics, today announced that an evaluation by the Walter Reed Army Institute of Research of the OraQuick® HCV Test, currently in clinical development by OraSure Technologies, was recently released at the Advanced Technology Applications for Combat Casualty Care meeting, sponsored by the Department of Defense.

Stanford Research Shows New Approach, Old Drug Show Promise Against Hepatitis C

Liver Disease / Hepatitis News From Medical News Today

The fight against the liver disease hepatitis C has been at something of an impasse for years, with more than 150 million people currently infected, and traditional antiviral treatments causing nasty side effects and often falling short of a cure. Using a novel technique, medical and engineering researchers at Stanford University have discovered a vulnerable step in the virus' reproduction process that in lab testing could be effectively targeted with an obsolete antihistamine.

Bristol-Myers Squibb Welcomes NICE Guidance Recommending Baraclude As Chronic Hepatitis B Treatment Option, UK

Liver Disease / Hepatitis News From Medical News Today

NICE (National Institute for Health and Clinical Excellence) has published guidance that recommends Baraclude(R) (entecavir) as an option for treatment of eligible patients with chronic hepatitis B (CHB).

ThermoDox® Liver Cancer Study Phase I Results To Be Presented At ILCA Conference 2008

Liver Disease / Hepatitis News From Medical News Today

CELSION CORPORATION (NASDAQ: CLSN) announced today that the interim results from its second Phase I liver cancer confirmation study of ThermoDox® used in combination with Radio Frequency Ablation (RFA) for the treatment of patients with primary and metastatic liver cancer will be presented at a Poster Presentation session at the International Liver Cancer Association (ILCA) Annual Conference in Chicago, IL, from September 5-7, 2008.

New Therapies Increasingly Being Used To Treat Liver Cancer

Liver Disease / Hepatitis News From Medical News Today

According to Millennium Research Group's (MRG) US Markets for Transcatheter Embolization and Occlusion Devices 2008 report, embolization particle therapies such as radioembolization spheres are increasingly being used to treat liver cancer.

Start Of Prolarix? Phase 2 Study In Liver Cancer

Liver Disease / Hepatitis News From Medical News Today

Protherics PLC ("Protherics" or the "Company"), the international biopharmaceutical company focused on critical care and cancer, announces the initiation of a phase 2a proof-of-concept study of Prolarix?, a targeted prodrug chemotherapy being developed for the treatment of primary liver cancer (hepatocellular carcinoma or "HCC").

NICE Issues Guidance On Treatments For Hepatitis B

Liver Disease / Hepatitis News From Medical News Today

The National Institute for Health and Clinical Excellence (NICE) has published final guidance on the use of Entecavir and Telbivudine for the treatment of chronic hepatitis B. NICE produced these two pieces of guidance as part of its rapid single technology appraisal (STA) work programme.

New Trial To Evaluate Nexavar® As Adjuvant Therapy In Liver Cancer

Liver Disease / Hepatitis News From Medical News Today

Bayer HealthCare Pharmaceuticals, Inc. and Onyx Pharmaceuticals, Inc. announced the start of a Phase III study with Nexavar® (sorafenib) tablets in liver cancer. The randomized, double-blind, placebo-controlled study is evaluating Nexavar as an adjuvant therapy for patients with hepatocellular carcinoma (HCC), or primary liver cancer. An adjuvant treatment is given as an additional systemic therapy after the initial tumor treatment, e.g.

Studies In Living Mice Demonstrate Senescent Liver Cells Can Provoke A Beneficial Immune Reaction

Liver Disease / Hepatitis News From Medical News Today

Although post-reproductive life in humans is often associated with decline and a loss of powers, an analogous state in certain cells -- called senescence -- is proving to be one of ironic potency. Scientists at Cold Spring Harbor Laboratory (CSHL) reported that a particular class of senescent liver cells orchestrates a sequence of events in living mice that can limit fibrosis, a natural response of the liver to acute damage.

Government Must Vaccinate All British Children Against Hepatitis, Association Of The British Pharmaceutical Industry

Liver Disease / Hepatitis News From Medical News Today

Patient groups are today calling on the Government to vaccinate all British children against Hepatitis B - a life threatening disease, 50 times more infectious than HIV. Chronic Hepatitis B can develop into potentially fatal conditions such as liver cancer and cirrhosis. It affects more than 325,000 patients in the UK alone, and once contracted cannot be cured. However, with a simple and effective vaccine, it can be prevented.

Body Puts Cells 'Under Arrest' To Protect Against Liver Disease

Liver Disease / Hepatitis News From Medical News Today

A stable form of cell-cycle arrest known to offer potent protection against cancer also limits liver fibrosis, a condition characterized by an excess of fibrous tissue, according to a new report in the August 22nd Cell, a Cell Press publication. Triggered by chronic liver damage produced by hepatitis infection, alcohol abuse, or fatty liver disease, liver fibrosis can lead to cirrhosis, a major health problem worldwide and the 12th most common cause of death in the United States.

Bayer And Onyx Begin Enrollment In STORM Trial Studying Nexavar As Adjuvant Therapy For Patients With Liver Cancer

Liver Disease / Hepatitis News From Medical News Today

Bayer HealthCare Pharmaceuticals, Inc. and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) announced the companies have begun enrolling patients in the STORM Sorafenib as Adjuvant Treatment in the Prevention of Recurrence of Hepatocellular Carcinoma trial.

Vertex Pharmaceuticals To Start Phase 3 'REALIZE' Trial With Telaprevir In Treatment-Failure HCV Patients

Liver Disease / Hepatitis News From Medical News Today

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) announced that the Company has reached agreement with U.S. and E.U. regulatory authorities to proceed with the REALIZE trial, a pivotal Phase 3 clinical trial with the hepatitis C virus (HCV) protease inhibitor telaprevir in combination therapy for patients with chronic HCV infection who failed to achieve a sustained viral response (SVR) with prior therapy. The trial will be conducted in the U.S. and E.U.

ViRexx Announces Encouraging Results From Its Lead ChimigenTM Therapeutic Vaccine Candidate For Treating Chronic Hepatitis B Virus Infections

Liver Disease / Hepatitis News From Medical News Today

ViRexx Medical Corp. (TSX:VIR) (AMEX:REX), company focused on developing innovative-targeted therapeutic products that offer better quality of life and a renewed hope for living.

Nasal Hepatitis B Vaccine Elicits Robust Immunity With A Single Dose; Confers Major Advantages Over Traditional Vaccines

Liver Disease / Hepatitis News From Medical News Today

A new study has shown that a nasal hepatitis B vaccine elicits a dramatic immune response in animals without requiring three vaccinations, sterile syringes or refrigeration-three factors that impede the delivery of current hepatitis B vaccines. In the study, a single dose of the nasal vaccine triggered a protective response in animals roughly 450 times greater than that elicited by currently approved human vaccines.

Nano Vaccine For Hepatitis B Shows Promise For Third World - Nanoemulsion Could Save More Lives By Removing Current Vaccines' Drawbacks

Liver Disease / Hepatitis News From Medical News Today

Chronic hepatitis B infects 400 million people worldwide, many of them children. Even with three effective vaccines available, hepatitis B remains a stubborn, unrelenting health problem, especially in Africa and other developing areas. The disease and its complications cause an estimated 1 million deaths globally each year. In many poor countries, refrigerated conditions required for the current vaccines are costly and hard to come by.

FDA Approves Viread(R) For Chronic Hepatitis B In Adults

Liver Disease / Hepatitis News From Medical News Today

Gilead Sciences, Inc. (NASDAQ:GILD) announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for Viread® (tenofovir disoproxil fumarate) for the treatment of chronic hepatitis B, a serious liver disease caused by the hepatitis B virus (HBV). Chronic hepatitis B is the leading cause of liver cancer worldwide and affects an estimated two million individuals in the United States.

U.S. Food And Drug Administration Approves Viread(R) For Chronic Hepatitis B In Adults

Liver Disease / Hepatitis News From Medical News Today

Gilead Sciences, Inc. (Nasdaq: GILD) announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for Viread® (tenofovir disoproxil fumarate) for the treatment of chronic hepatitis B, a serious liver disease caused by the hepatitis B virus (HBV). Chronic hepatitis B is the leading cause of liver cancer worldwide and affects an estimated two million individuals in the United States.

Metabasis Therapeutics Collaborates With Roche To Develop Liver-Targeted Compounds For The Treatment Of Hepatitis C

Liver Disease / Hepatitis News From Medical News Today

Metabasis Therapeutics, Inc. (Nasdaq:MBRX) announced that it has entered into a two-year research collaboration agreement with Roche to apply Metabasis' HepDirect® liver-targeting technology to Roche's proprietary lead nucleosides in order to develop new treatments for hepatitis C virus (HCV). Under the terms of the agreement, Roche will provide a $10 million upfront payment.

Early Treatment Is Key To Combating Hepatitis C Virus - Researchers Publish Research Results In Online Edition Of Journal Of Virology

Liver Disease / Hepatitis News From Medical News Today

Canadian researchers have shown that patients who receive early treatment for Hepatitis C virus (HCV) within the first months following an infection, develop a rapid poly-functional immune response against HCV similar to when infection is erradicted spontaneously, according to a new study published in the Journal of Virology. Therefore, early treatment can restore immune response against HCV and help eliminate the virus rapidly.

Phase 3 Trial With Investigational Hepatitis B Vaccine (HEPLISAV) Met Primary Endpoint

Liver Disease / Hepatitis News From Medical News Today

Dynavax Technologies Corporation (Nasdaq:DVAX) and Merck & Co., Inc. announced today top-line immunogenicity results from a Phase 3 clinical trial comparing HEPLISAV?, an investigational hepatitis B virus (HBV) vaccine, to a currently marketed HBV vaccine, Engerix-B® (1). The study achieved its primary endpoint. HEPLISAV is being jointly developed by Dynavax and Merck for use in adults and in patients with end stage renal disease.

Pharmasset Reports Preliminary Results Of A 4-week Combination Study Of R7128 For The Treatment Of Chronic Hepatitis C

Liver Disease / Hepatitis News From Medical News Today

Pharmasset, Inc. (Nasdaq: VRUS) announces the preliminary results of the third cohort of a 4-week Phase 1 clinical trial evaluating R7128 1000mg twice daily (BID) in combination with the standard of care (SOC), Pegasys(R) (pegylated interferon) plus Copegus(R) (ribavirin), in 31 treatment-naive patients chronically infected with hepatitis C virus (HCV) genotype 1.

What Bugs Mosquitoes? Smelling DEET

MedicineNet Infectious Disease General

Title: What Bugs Mosquitoes? Smelling DEET
Category: Health News
Created: 8/25/2008
Last Editorial Review: 8/25/2008

One-Year Recovery for West Nile Virus

MedicineNet Infectious Disease General

Title: One-Year Recovery for West Nile Virus
Category: Health News
Created: 8/19/2008
Last Editorial Review: 8/19/2008

New Test Scans Beef for Mad Cow Disease

MedicineNet Infectious Disease General

Title: New Test Scans Beef for Mad Cow Disease
Category: Health News
Created: 8/13/2008 9:18:00 AM
Last Editorial Review: 8/13/2008

Low Blood Pressure

MedicineNet Infectious Disease General

Title: Low Blood Pressure
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 8/7/2008

Researchers Find Genes That Influence West Nile Virus

MedicineNet Infectious Disease General

Title: Researchers Find Genes That Influence West Nile Virus
Category: Health News
Created: 8/7/2008 2:00:00 AM
Last Editorial Review: 8/7/2008

Ingrown Toenail

MedicineNet Infectious Disease General

Title: Ingrown Toenail
Category: Diseases and Conditions
Created: 8/5/2008
Last Editorial Review: 8/5/2008

Dehydration

MedicineNet Infectious Disease General

Title: Dehydration
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 7/28/2008

Diabetes

MedicineNet Infectious Disease General

Title: Diabetes
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 7/22/2008

Fever

MedicineNet Infectious Disease General

Title: Fever
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 7/22/2008

Mycobacterium Marinum

MedicineNet Infectious Disease General

Title: Mycobacterium Marinum
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 7/18/2008

Detecting Hearing Loss in Children

MedicineNet Infectious Disease General

Title: Detecting Hearing Loss in Children
Category: Procedures and Tests
Created: 10/30/2002
Last Editorial Review: 7/18/2008

Genetic Trait Boosts AIDS Risks in Blacks

MedicineNet Infectious Disease General

Title: Genetic Trait Boosts AIDS Risks in Blacks
Category: Health News
Created: 7/17/2008 2:00:00 AM
Last Editorial Review: 7/17/2008

Direct-to-Consumer Drug Ads Have Little Effect on Sales: Study

MedicineNet Digestion General

Title: Direct-to-Consumer Drug Ads Have Little Effect on Sales: Study
Category: Health News
Created: 9/3/2008 2:00:00 AM
Last Editorial Review: 9/3/2008

Protecting Newborns From a Dangerous Threat

MedicineNet Digestion General

Title: Protecting Newborns From a Dangerous Threat
Category: Health News
Created: 8/29/2008 2:00:00 AM
Last Editorial Review: 8/29/2008

Cadmium Exposure Tied to Lung Disease

MedicineNet Digestion General

Title: Cadmium Exposure Tied to Lung Disease
Category: Health News
Created: 8/29/2008 2:00:00 AM
Last Editorial Review: 8/29/2008

Dalai Lama's Exhaustion: FAQ

MedicineNet Digestion General

Title: Dalai Lama's Exhaustion: FAQ
Category: Health News
Created: 8/29/2008
Last Editorial Review: 8/29/2008

Salmonella Outbreak Appears to Be Over

MedicineNet Digestion General

Title: Salmonella Outbreak Appears to Be Over
Category: Health News
Created: 8/29/2008
Last Editorial Review: 8/29/2008

6 Deaths Reported From Diabetes Drug Byetta

MedicineNet Digestion General

Title: 6 Deaths Reported From Diabetes Drug Byetta
Category: Health News
Created: 8/28/2008
Last Editorial Review: 8/28/2008

Nuts Don't Up Risk of Diverticulitis

MedicineNet Digestion General

Title: Nuts Don't Up Risk of Diverticulitis
Category: Health News
Created: 8/27/2008
Last Editorial Review: 8/27/2008

Health Tip: Feeling Thirsty?

MedicineNet Digestion General

Title: Health Tip: Feeling Thirsty?
Category: Health News
Created: 8/26/2008 2:00:00 AM
Last Editorial Review: 8/26/2008

For Rare Blood Disorder, Pumping Iron Is the Cure

MedicineNet Digestion General

Title: For Rare Blood Disorder, Pumping Iron Is the Cure
Category: Health News
Created: 8/26/2008 2:00:00 AM
Last Editorial Review: 8/26/2008

Alzheimer's Disease Patient Caregiver Guide

MedicineNet Digestion General

Title: Alzheimer's Disease Patient Caregiver Guide
Category: Diseases and Conditions
Created: 8/26/2008
Last Editorial Review: 8/26/2008

Molecule Keeps Bacteria Like Salmonella in Check

MedicineNet Digestion General

Title: Molecule Keeps Bacteria Like Salmonella in Check
Category: Health News
Created: 8/23/2008 2:00:00 AM
Last Editorial Review: 8/25/2008

Gastric Band Weight-Loss Surgery Can Boost Reflux

MedicineNet Digestion General

Title: Gastric Band Weight-Loss Surgery Can Boost Reflux
Category: Health News
Created: 8/23/2008 2:00:00 AM
Last Editorial Review: 8/25/2008

Alcohol-illusion: Alcohol and Energy Drinks Combo, Maintains Sobriety?