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Arthritis News
Arthritis / Rheumatology News From Medical News Today
MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) and the University of Melbourne announced today an agreement to cooperate on investigating new therapeutic applications for MorphoSys's MOR103 program. MOR103, a HuCAL antibody against human GM-CSF (Granulocyte macrophage-colony stimulating factor), is currently in development for the treatment of rheumatoid arthritis (RA).
Arthritis / Rheumatology News From Medical News Today
POZEN Inc. (NASDAQ:POZN), announced the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for the marketing approval of VIMOVO? (PN 400), the combination of enteric coated (EC) naproxen and immediate release esomeprazole. POZEN and AstraZeneca entered into a global co-development agreement for VIMOVO in August 2006.
Arthritis / Rheumatology News From Medical News Today
Lyme disease in the U.S. is caused by the tick-borne bacteria Borrelia burgdorferi and usually begins with a skin lesion, after which the bacteria spread throughout the body to the nervous system, heart or joints. About 60 percent of untreated individuals develop arthritis, which affects the knees in particular.
Arthritis / Rheumatology News From Medical News Today
Treatment with anti-tumor necrosis factor (TNF) agents is recognized as a risk factor for tuberculosis (TB) in patients with immune-mediated inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, psoriatic arthritis and psoriasis. Most TB cases develop as a result of reactivation of a latent TB infection, and health authorities worldwide recommend screening for latent TB and treating patients before initiating anti-TNF treatment.
Arthritis / Rheumatology News From Medical News Today
Aclasta® (zoledronic acid 5 mg)[1] has been approved in the European Union to treat men and post-menopausal women with osteoporosis caused by the long-term use of glucocorticoids, commonly known as steroids.
Arthritis / Rheumatology News From Medical News Today
A new computer model developed at MIT can help solve a problem that has plagued drug companies trying to develop promising new treatments made of antibodies: Such drugs have a relatively short shelf life because they tend to clump together, rendering them ineffective. Antibodies are the most rapidly growing class of human drugs, with the potential to treat cancer, arthritis and other chronic inflammatory and infectious diseases.
Arthritis / Rheumatology News From Medical News Today
Scientists have discovered gene expression differences that could lead to better ways to classify, predict outcome, and treat juvenile idiopathic arthritis (JIA). Eventually such findings could enable doctors to target more aggressive treatment to children at risk of more severe arthritis, while those likely to have milder disease could be spared the stronger treatments that carry a greater risk of side effects.
Arthritis / Rheumatology News From Medical News Today
A signal molecule made by the human body that triggers the immune system into action may be important in rheumatoid arthritis, according to new research published in Nature Medicine. The authors of the study, from Imperial College London, say that if scientists could block this signal, it may be possible to develop more effective arthritis treatments. Rheumatoid arthritis is the most common autoimmune disease, affecting around 1 in 100 people.
Arthritis / Rheumatology News From Medical News Today
An article published Online First and in this week's edition of reports information about Golimumab, a new tumour necrosis factor-α (TNF-α) inhibitor. It reduces the signs and symptoms of rheumatoid arthritis in patients who have previously received any other TNF-α inhibitor. This drug might be a good alternative for patients who have inadequate responses to one or two other TNF-α inhibitors. Over three million people in Europe and about 1.
Arthritis / Rheumatology News From Medical News Today
A clinical trial of masitinib, a drug in development for the treatment of rheumatoid arthritis, has shown it to be well tolerated and effective. Researchers writing in BioMed Central's open access journal Arthritis Research and Therapy have shown that treatment with masitinib significantly reduced the severity of active arthritis.
Arthritis / Rheumatology News From Medical News Today
According to a new study from researchers at Duke University, total knee arthroplasty (TKA) procedures performed in older patients with osteoarthritis of the knee result in long-term, significant improvement of physical functioning and motor skills when compared to patients who do not receive TKA.
Arthritis / Rheumatology News From Medical News Today
UCB announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA) has issued a positive opinion recommending that the European Commission grants a marketing authorisation for Cimzia® (certolizumab pegol), in combination with methotrexate (MTX), for the treatment of moderate to severe active rheumatoid arthritis in adult patients when the response to disease-modifying anti-rheumatic drugs (DMARDs) including MTX, has been inadequate.
Arthritis / Rheumatology News From Medical News Today
The Rheumatology Futures Project and the Department of Health have launched a new 18-week commissioning pathway for inflammatory arthritis (IA).
Arthritis / Rheumatology News From Medical News Today
MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) today announced that the Company has submitted an application for the authorization of a phase 1b/2a clinical study in patients with active rheumatoid arthritis (RA) for its lead drug MOR103, a fully human HuCAL-derived monoclonal antibody directed against Granulocyte Macrophage-Colony Stimulating Factor.
Arthritis / Rheumatology News From Medical News Today
According to the CDC, 46 million Americans were told by a doctor they have arthritis, the leading cause of disability in the United States. Flexcin International, Inc., a natural supplement company offering the only joint pain remedy products with CM8?, offers arthritis and bursitis treatment for anyone suffering from pain-related disease and injuries.
Arthritis / Rheumatology News From Medical News Today
Neovacs, a biotechnology company developing proprietary immunotherapeutics for autoimmune and chronic diseases, announced that subject to regulatory consent, it plans to initiate a Phase II study of its TNF-alpha Kinoid later this year in rheumatoid arthritis patients who have failed treatment with at least one TNF-alpha inhibitor. The decision to proceed with the trial was based on an initial review of encouraging data from the company's Phase I/II study in Crohn's disease.
Arthritis / Rheumatology News From Medical News Today
The health and physiological effects of an intervention which facilitates the opening of feelings are described in a paper published in the current issue of Psychotherapy and Psychosomatics. The efficacy of emotional disclosure in alleviating psychological and physical stress has been well documented in controlled laboratory studies. A next step is to evaluate its clinical utility in 'real world' settings.
Arthritis / Rheumatology News From Medical News Today
How molecules of the oldest branch of the human immune system have interconnected has remained a mystery. Now, two new structures, both involving a central component of an enzyme important to the complement system of the immune response, reveal how this system fights invading microbes while avoiding problems of the body attacking itself.
Arthritis / Rheumatology News From Medical News Today
A new study by The George Institute for International Health has found Tai Chi to have positive health benefits for musculoskeletal pain. The results of the first comprehensive analysis of Tai Chi suggest that it produces positive effects for improving pain and disability among arthritis sufferers. The researchers are now embarking on a new trial to establish if similar benefits can be seen among people with chronic low back pain.
Arthritis / Rheumatology News From Medical News Today
Celgene Corporation (NASDAQ: CELG) announced the preliminary results of a phase II, multi-center, randomized, double-blind, placebo-controlled, three-arm study of apremilast - a novel, orally available small molecule that exhibits anti- inflammatory activities through the suppression of multiple pro-inflammatory mediators and cytokines - in adult patients with psoriatic arthritis (CC-10004-PSA-001). The study met its primary objective of assessment of ACR20 at 12 weeks.
Arthritis / Rheumatology News From Medical News Today
Over half (63%) of patients with rheumatoid arthritis (RA) also suffer from psychiatric disorders, with the majority of these (87%) occurring in the depressive spectrum, according to the results of a new study presented recently at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark. Interestingly, over half (52%) of the patients studied indicated that they had experienced stress events before the onset of their RA.
Arthritis / Rheumatology News From Medical News Today
Proteolix, Inc. announced that in an article published in Nature Medicine, Proteolix's selective immunoproteasome inhibitor PR-957 was shown to block disease progression in mouse models of rheumatoid arthritis in a dose-dependent manner and to completely eliminate visible signs of disease at the highest dose. The anti-inflammatory effect induced by PR-957 was rapid and long-lasting, lowering expression of multiple inflammatory mediators, including TNF-a and IL-6.
Arthritis / Rheumatology News From Medical News Today
Patients with rheumatic diseases want more information and better communication with healthcare professionals on the sexual issues related to their conditions, according to the results of a new study presented recently at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark.
Arthritis / Rheumatology News From Medical News Today
First line treatment with anakinra (an interleukin-1 (IL-1) receptor antagonist), results in a 'good' clinical response (ACRp90) in patients newly diagnosed with systemic onset juvenile idiopathic arthritis (SoJIA), and restores the deficient IL-18 response of natural killer (NK) cells*, according to a new study presented recently at PReS 2009, a joint congress with the 2009 Congress of the European League Against Rheumatism (EULAR) in Copenhagen, Denmark.
Arthritis / Rheumatology News From Medical News Today
When a patient's first symptoms of rheumatoid arthritis (RA) occur in winter, the severity of their RA (as measured by the modified Total Sharp Score, mTSS, an assessment of erosion and joint space narrowing) was rated more severe at six months, when compared to patients whose RA first became symptomatic in summer (Odds Ratio (OR) =2.82 [1.14;7], p=0.0255).
MedicineNet Arthritis General
Title: Health Tip: What's Causing My Neck Pain?
Category: Health News
Created: 7/2/2009 7:00:00 AM
Last Editorial Review: 7/2/2009
Category: Health News
Created: 7/2/2009 7:00:00 AM
Last Editorial Review: 7/2/2009
MedicineNet Arthritis General
Title: Celiac Disease Cases Are on the Rise
Category: Health News
Created: 7/2/2009
Last Editorial Review: 7/2/2009
Category: Health News
Created: 7/2/2009
Last Editorial Review: 7/2/2009
MedicineNet Arthritis General
Title: Kidney Stones
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 6/30/2009
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 6/30/2009
MedicineNet Arthritis General
Title: Disease Prevention in Women
Category: Diseases and Conditions
Created: 3/22/2001 7:23:00 AM
Last Editorial Review: 6/30/2009
Category: Diseases and Conditions
Created: 3/22/2001 7:23:00 AM
Last Editorial Review: 6/30/2009
MedicineNet Arthritis General
Title: Discovery Points to Regulation of Calcium Metabolism
Category: Health News
Created: 6/30/2009 7:00:00 AM
Last Editorial Review: 6/30/2009
Category: Health News
Created: 6/30/2009 7:00:00 AM
Last Editorial Review: 6/30/2009
MedicineNet Arthritis General
Title: Rheumatoid Arthritis: New Treatment Target?
Category: Health News
Created: 6/30/2009
Last Editorial Review: 6/30/2009
Category: Health News
Created: 6/30/2009
Last Editorial Review: 6/30/2009
MedicineNet Arthritis General
Title: Spondylolisthesis
Category: Diseases and Conditions
Created: 6/30/2009
Last Editorial Review: 6/30/2009
Category: Diseases and Conditions
Created: 6/30/2009
Last Editorial Review: 6/30/2009
MedicineNet Arthritis General
Title: Lyme Disease
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 6/29/2009
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 6/29/2009
MedicineNet Arthritis General
Title: New Drug Shows Promise for Rheumatoid Arthriitis
Category: Health News
Created: 6/28/2009 7:00:00 AM
Last Editorial Review: 6/29/2009
Category: Health News
Created: 6/28/2009 7:00:00 AM
Last Editorial Review: 6/29/2009
MedicineNet Arthritis General
Title: Sudden Cardiac Arrest
Category: Diseases and Conditions
Created: 1/31/2005 10:49:00 AM
Last Editorial Review: 6/25/2009
Category: Diseases and Conditions
Created: 1/31/2005 10:49:00 AM
Last Editorial Review: 6/25/2009
MedicineNet Arthritis General
Title: Cardiac Arrest Symptoms and Causes
Category: Doctor's Views
Created: 1/27/2006
Last Editorial Review: 6/25/2009
Category: Doctor's Views
Created: 1/27/2006
Last Editorial Review: 6/25/2009
MedicineNet Arthritis General
Title: Bone Therapy May Not Always Need Monitoring
Category: Health News
Created: 6/25/2009 7:00:00 AM
Last Editorial Review: 6/25/2009
Category: Health News
Created: 6/25/2009 7:00:00 AM
Last Editorial Review: 6/25/2009
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